Vitamin d3 good for weight loss
Associated with vitamin D deficiency, leading to rickets. a. Dermal synthesis of vitamin D from cholesterol is dependent on sun exposure (specifically UVB radiation ). Mixture of molecular compounds of ergocalciferol with lumisterol, 1:1. Without sufficient vitamin D, bones can become thin, brittle, or misshapen. Pregnant or breastfeeding women should consult a doctor before taking a vitamin D supplement. Generally considered inadequate for bone and overall health. Serum 25(OH)D levels do not indicate the amount of vitamin D stored in body tissues. The main symptoms of vitamin D overdose which can occur are those of hypercalcemia. Together with calcium, vitamin D also helps protect older adults from osteoporosis. Osteomalacia is a disease in adults that results from vitamin D deficiency. k. Vitamin D toxicity is treated by discontinuing vitamin D supplementation and restricting calcium intake. In the liver, cholecalciferol (vitamin D 3 ) is converted to calcifediol. Many cells have vitamin D receptors, and some convert 25(OH)D to 1,25(OH) 2 D. Vitamin D refers to a group of fat-soluble secosteroids responsible for increasing intestinal absorption of calcium, iron, magnesium, phosphate, and zinc. Serum concentration of 25(OH)D is the best indicator of vitamin D status.
Vitamin D has a significant role in calcium homeostasis and metabolism. Vitamin D promotes calcium absorption in the gut and maintains adequate serum calcium and phosphate concentrations to enable normal mineralization of bone and to prevent hypocalcemic tetany. Evidence indicates the synthesis of vitamin D from sun exposure is regulated by a negative feedback loop that prevents toxicity, but because of uncertainty about the cancer risk from sunlight, no recommendations are issued by the Institute of Medicine (US) for the amount of sun exposure required to reach vitamin D requirements. Rickets, a childhood disease, is characterized by impeded growth and soft, weak, deformed long bones that bend and bow under their weight as children start to walk. Table of Contents Introduction Reference Intakes Sources of Vitamin D Vitamin D Intakes and Status Vitamin D Deficiency Groups at Risk of Vitamin D Inadequacy Vitamin D and Health Health Risks from Excessive Vitamin D Interactions with Medications Vitamin D and Healthful Diets References Disclaimer. Several forms ( vitamers ) of vitamin D exist. It is also produced endogenously when ultraviolet rays from sunlight strike the skin and trigger vitamin D synthesis. Ergocalciferol (vitamin D 2 ) is converted in the liver to 25-hydroxyergocalciferol (a. Vitamin D is a fat-soluble vitamin that is naturally present in very few foods, added to others, and available as a dietary supplement. A diet deficient in vitamin D in conjunction with inadequate sun exposure causes osteomalacia (or rickets when it occurs in children), which is a softening of the bones. Emerging evidence links potential adverse effects to such. g. An additional complication in assessing vitamin D status is in the actual measurement of serum 25(OH)D concentrations. For more details on this topic, see hypervitaminosis D. 25-hydroxyvitamin D 2 — abbreviated 25(OH)D 2 ). Generally considered adequate for bone and overall health. Vitamin D obtained from sun exposure, food, and supplements is biologically inert and must undergo two hydroxylations in the body for activation. The FDA advised manufacturers of liquid vitamin D supplements that droppers accompanying these products should be clearly and accurately marked for 400 international units (IU). There is considerable discussion of the serum concentrations of 25(OH)D associated with deficiency (e. , rickets), adequacy for bone health, and optimal overall health, and cut points have not been developed by a scientific consensus process.
